Lipkin教授提出了針對新型冠狀病毒感染的肺炎疫情防控關鍵的13問,如下:
1.What is the strategy for identifying contactsof infected people?
1.用什么方法確認與病毒感染者接觸過的人員?
2. What are the case definition criteria?
2.確診感染病例的定義標準是什么?
3. What is the incubation period (mean, range)?How was it determined?
3.病毒潛伏期是多少(平均值,范圍)?如何確定的?
4. What is the course of illness for mild,severe and fatal cases?
4.輕癥、重癥和致死病例的病程各自情況如何?
5. What is the time of onset and duration ofvirus shedding? How was this determined? Where is virus found: blood, saliva,sputum, feces?Who is tested for infection? How are theytested?Are the methods used for identifying cases,examining contacts, testing for virus and treatment consistent across sites inWuhan? In China?
5.病毒的發作時間和傳播過程需要的時間是多少?如何確定的?在哪里發現病毒:血液,唾液,痰,糞便?對哪些人進行了感染檢測?如何檢測他們?在武漢的各個站點之間用于識別病例,檢查病人接觸人員,測試病毒和治療的方法是否一致?在全國范圍內?
6. What proportion of cases outside of Wuhan donot have Wuhan exposure?
6.武漢地區以外無武漢接觸史的病例比例是多少?
7. What is the range of disease severity by age?
7.按年齡劃分疾病嚴重程度的范圍是多少?
8. What is the evidence to support the claim ofpre-symptomatic shedding?
8.聲稱癥狀發作前的病毒散播有何支撐證據?
9. What is the evidence of zoonotic exposure inpatients? What percentage went to animal markets?
9.病人中因接觸動物致病的證據是什么?病人中去過野生動物市場的比例是多少?
10. What is the percentage of negative testresults?
10.測試結果陰性的百分比是多少?
11. What types of health care workers are athigh risk? At low risk? What percentage of health workers have become infected?
11.哪些類型的醫護人員處于感染高風險?低風險?被感染的醫護人員的百分比是多少?
12. Is there evidence of fomite transmission?
12.是否有病媒傳播的證據?
13. Is there evidence of ‘super spreaders?
13.是否有超級病毒傳播者的證據?
是否能回答這13個問題,正好驗證我們在2003年以后建立的傳染病防控體系的有效性。同時,在此次的會議中,中山大學陸家海團隊與哥倫比亞大學的國際合作項目正式啟動,將開展流行病學溯源、預測、診斷研